Tetrahydrofuran (THF) is a heterocyclic compound (cyclic ether). It is colorless, has low viscosity, and good solubility in a wide range of solvents. It is widely used as a solvent in org-anic synthesis, being very popular in reactions with org-anometallic compounds and Grignard reagents. Due to org-anic peroxides formation on long term storage, THF is usually stabilized by adding butylated hydroxytoluene (BHT). BHT removes the free radicals required for the peroxide formation.
Application
Tetrahydrofuran (THF) is used as a solvent in the following processes:
- Org-anic synthesis
- a) Grignard
- b) Org-anometallic compounds
- c) Reformatsky
- d) Lithiation
- e) Hydride reduction
- f) Metal-catalyzed coupling (Heck, Stile, Suzuki)
- g) Lewis acid mediated reactions
ACS solvents meet or exceed the high standards of the American Chemical Society (ACS),with test specifications that are specialized to every compound. According to the American Chemical Society, ACS reagent grade implies that it is a substance of sufficient purity to be used in most chemical analyses or reactions.
| Unit of Measure | Pack of 4 pcs |
